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BIGDAWG: Case-Control Analysis of Multi-Allelic Loci

Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.

Version: 3.0.3
Depends: R (≥ 3.5.0)
Imports: XML, httr, haplo.stats, parallel
Suggests: knitr, rmarkdown
Published: 2021-11-17
DOI: 10.32614/CRAN.package.BIGDAWG
Author: Derek Pappas, Steve Mack, Jill Hollenbach
Maintainer: Steve Mack <Steven.Mack at ucsf.edu>
BugReports: https://github.com/IgDAWG/BIGDAWG/issues
License: GPL (≥ 3)
URL: http://tools.immunogenomics.org/, https://github.com/IgDAWG/BIGDAWG
NeedsCompilation: no
Materials: NEWS
CRAN checks: BIGDAWG results

Documentation:

Reference manual: BIGDAWG.pdf
Vignettes: BIGDAWG
GLSconvert

Downloads:

Package source: BIGDAWG_3.0.3.tar.gz
Windows binaries: r-devel: BIGDAWG_3.0.3.zip, r-release: BIGDAWG_3.0.3.zip, r-oldrel: BIGDAWG_3.0.3.zip
macOS binaries: r-release (arm64): BIGDAWG_3.0.3.tgz, r-oldrel (arm64): BIGDAWG_3.0.3.tgz, r-release (x86_64): BIGDAWG_3.0.3.tgz, r-oldrel (x86_64): BIGDAWG_3.0.3.tgz
Old sources: BIGDAWG archive

Reverse dependencies:

Reverse imports: pould, SSHAARP

Linking:

Please use the canonical form https://CRAN.R-project.org/package=BIGDAWG to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.