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FIND: Objective Comparison of Phase I Dose-Finding Designs

Generate decision tables and simulate operating characteristics for phase I dose-finding designs to enable objective comparison across methods. Supported designs include the traditional 3+3, Bayesian Optimal Interval (BOIN) (Liu and Yuan (2015) <doi:10.1158/1078-0432.CCR-14-1526>), modified Toxicity Probability Interval-2 (mTPI-2) (Guo et al. (2017) <doi:10.1002/sim.7185>), interval 3+3 (i3+3) (Liu et al. (2020) <doi:10.1177/0962280220939123>), and Generalized 3+3 (G3). Provides visualization tools for comparing decision rules and operating characteristics across multiple designs simultaneously.

Version: 0.1.1
Imports: ggplot2, grid, gridExtra, gtable, dplyr, rlang, stats
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2025-12-15
DOI: 10.32614/CRAN.package.FIND
Author: Yuan Ji [aut], Yunxuan Zhang [aut, cre]
Maintainer: Yunxuan Zhang <yunxuanz at uchicago.edu>
License: MIT + file LICENSE
NeedsCompilation: no
Language: en-US
Materials: NEWS
CRAN checks: FIND results

Documentation:

Reference manual: FIND.html , FIND.pdf
Vignettes: FIND Package Guidance (source, R code)

Downloads:

Package source: FIND_0.1.1.tar.gz
Windows binaries: r-devel: FIND_0.1.1.zip, r-release: FIND_0.1.1.zip, r-oldrel: FIND_0.1.1.zip
macOS binaries: r-release (arm64): FIND_0.1.1.tgz, r-oldrel (arm64): FIND_0.1.1.tgz, r-release (x86_64): FIND_0.1.1.tgz, r-oldrel (x86_64): FIND_0.1.1.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=FIND to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.