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Statistical testing procedures for detecting GxE (gene-environment) interactions. The main focus lies on GRSxE interaction tests that aim at detecting GxE interactions through GRS (genetic risk scores). Moreover, a novel testing procedure based on bagging and OOB (out-of-bag) predictions is implemented for incorporating all available observations at both GRS construction and GxE testing (Lau et al., 2023, <doi:10.1038/s41598-023-28172-4>).
Version: | 1.0.1 |
Imports: | glmnet, ranger, stats, utils |
Published: | 2023-10-30 |
DOI: | 10.32614/CRAN.package.GRSxE |
Author: | Michael Lau [aut, cre] |
Maintainer: | Michael Lau <michael.lau at hhu.de> |
License: | MIT + file LICENSE |
NeedsCompilation: | no |
Materials: | README |
CRAN checks: | GRSxE results |
Reference manual: | GRSxE.pdf |
Package source: | GRSxE_1.0.1.tar.gz |
Windows binaries: | r-devel: GRSxE_1.0.1.zip, r-release: GRSxE_1.0.1.zip, r-oldrel: GRSxE_1.0.1.zip |
macOS binaries: | r-release (arm64): GRSxE_1.0.1.tgz, r-oldrel (arm64): GRSxE_1.0.1.tgz, r-release (x86_64): GRSxE_1.0.1.tgz, r-oldrel (x86_64): GRSxE_1.0.1.tgz |
Old sources: | GRSxE archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.