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GenTwoArmsTrialSize: Generalized Two Arms Clinical Trial Sample Size Calculation

Two arms clinical trials required sample size is calculated in the comprehensive parametric context. The calculation is based on the type of endpoints(continuous/binary/time-to-event/ordinal), design (parallel/crossover), hypothesis tests (equality/noninferiority/superiority/equivalence), trial arms noncompliance rates and expected loss of follow-up. Methods are described in: Chow SC, Shao J, Wang H, Lokhnygina Y (2017) <doi:10.1201/9781315183084>, Wittes, J (2002) <doi:10.1093/epirev/24.1.39>, Sato, T (2000) <doi:10.1002/1097-0258(20001015)19:19%3C2689::aid-sim555%3E3.0.co;2-0>, Lachin J M, Foulkes, M A (1986) <doi:10.2307/2531201>, Whitehead J(1993) <doi:10.1002/sim.4780122404>, Julious SA (2023) <doi:10.1201/9780429503658>.

Version: 0.0.5
Imports: TrialSize, dplyr, Hmisc
Suggests: knitr, rmarkdown
Published: 2024-03-16
DOI: 10.32614/CRAN.package.GenTwoArmsTrialSize
Author: Mohsen Soltanifar ORCID iD [aut], Chel Hee Lee ORCID iD [cre, aut]
Maintainer: Chel Hee Lee <chelhee.lee at ucalgary.ca>
License: GPL-3
NeedsCompilation: no
CRAN checks: GenTwoArmsTrialSize results

Documentation:

Reference manual: GenTwoArmsTrialSize.pdf
Vignettes: tutorial

Downloads:

Package source: GenTwoArmsTrialSize_0.0.5.tar.gz
Windows binaries: r-devel: GenTwoArmsTrialSize_0.0.5.zip, r-release: GenTwoArmsTrialSize_0.0.5.zip, r-oldrel: GenTwoArmsTrialSize_0.0.5.zip
macOS binaries: r-release (arm64): GenTwoArmsTrialSize_0.0.5.tgz, r-oldrel (arm64): GenTwoArmsTrialSize_0.0.5.tgz, r-release (x86_64): GenTwoArmsTrialSize_0.0.5.tgz, r-oldrel (x86_64): GenTwoArmsTrialSize_0.0.5.tgz
Old sources: GenTwoArmsTrialSize archive

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.