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Two arms clinical trials required sample size is calculated in the comprehensive parametric context. The calculation is based on the type of endpoints(continuous/binary/time-to-event/ordinal), design (parallel/crossover), hypothesis tests (equality/noninferiority/superiority/equivalence), trial arms noncompliance rates and expected loss of follow-up. Methods are described in: Chow SC, Shao J, Wang H, Lokhnygina Y (2017) <doi:10.1201/9781315183084>, Wittes, J (2002) <doi:10.1093/epirev/24.1.39>, Sato, T (2000) <doi:10.1002/1097-0258(20001015)19:19%3C2689::aid-sim555%3E3.0.co;2-0>, Lachin J M, Foulkes, M A (1986) <doi:10.2307/2531201>, Whitehead J(1993) <doi:10.1002/sim.4780122404>, Julious SA (2023) <doi:10.1201/9780429503658>.
Version: | 0.0.5 |
Imports: | TrialSize, dplyr, Hmisc |
Suggests: | knitr, rmarkdown |
Published: | 2024-03-16 |
DOI: | 10.32614/CRAN.package.GenTwoArmsTrialSize |
Author: | Mohsen Soltanifar |
Maintainer: | Chel Hee Lee <chelhee.lee at ucalgary.ca> |
License: | GPL-3 |
NeedsCompilation: | no |
CRAN checks: | GenTwoArmsTrialSize results |
Reference manual: | GenTwoArmsTrialSize.pdf |
Vignettes: |
tutorial |
Package source: | GenTwoArmsTrialSize_0.0.5.tar.gz |
Windows binaries: | r-devel: GenTwoArmsTrialSize_0.0.5.zip, r-release: GenTwoArmsTrialSize_0.0.5.zip, r-oldrel: GenTwoArmsTrialSize_0.0.5.zip |
macOS binaries: | r-release (arm64): GenTwoArmsTrialSize_0.0.5.tgz, r-oldrel (arm64): GenTwoArmsTrialSize_0.0.5.tgz, r-release (x86_64): GenTwoArmsTrialSize_0.0.5.tgz, r-oldrel (x86_64): GenTwoArmsTrialSize_0.0.5.tgz |
Old sources: | GenTwoArmsTrialSize archive |
Please use the canonical form https://CRAN.R-project.org/package=GenTwoArmsTrialSize to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.