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It provides functions to design historical controlled trials with survival outcome by group sequential method. The options for interim look boundaries are efficacy only, efficacy & futility or futility only. It also provides the function to monitor the trial for any unplanned look. The package is based on Jianrong Wu, Xiaoping Xiong (2016) <doi:10.1002/pst.1756> and Jianrong Wu, Yimei Li (2020) <doi:10.1080/10543406.2019.1684305>.
Version: | 0.7.2 |
Imports: | Rdpack, diversitree, mvtnorm, flexsurv, stats, survival, crayon |
Published: | 2022-11-17 |
DOI: | 10.32614/CRAN.package.HCTDesign |
Author: | Tushar Patni [aut, cre], Yimei Li [aut], Jianrong Wu [aut], Arzu Onar-Thomas [aut] |
Maintainer: | Tushar Patni <patni006 at umn.edu> |
License: | GPL-3 |
NeedsCompilation: | no |
CRAN checks: | HCTDesign results |
Reference manual: | HCTDesign.pdf |
Package source: | HCTDesign_0.7.2.tar.gz |
Windows binaries: | r-devel: HCTDesign_0.7.2.zip, r-release: HCTDesign_0.7.2.zip, r-oldrel: HCTDesign_0.7.2.zip |
macOS binaries: | r-release (arm64): HCTDesign_0.7.2.tgz, r-oldrel (arm64): HCTDesign_0.7.2.tgz, r-release (x86_64): HCTDesign_0.7.2.tgz, r-oldrel (x86_64): HCTDesign_0.7.2.tgz |
Old sources: | HCTDesign archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.