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The proportion of cancer cells in solid tumor sample, known as the tumor purity, has adverse impact on a variety of data analyses if not properly accounted for. We develop 'InfiniumPurify', which is a comprehensive R package for estimating and accounting for tumor purity based on DNA methylation Infinium 450k array data. 'InfiniumPurify' provides functionalities for tumor purity estimation. In addition, it can perform differential methylation detection and tumor sample clustering with the consideration of tumor purities.
| Version: | 1.3.1 |
| Depends: | matrixStats |
| Published: | 2017-01-14 |
| DOI: | 10.32614/CRAN.package.InfiniumPurify |
| Author: | Yufang Qin |
| Maintainer: | Yufang Qin <yfqin at shou.edu.cn> |
| License: | GPL-2 |
| NeedsCompilation: | no |
| CRAN checks: | InfiniumPurify results |
| Reference manual: | InfiniumPurify.pdf |
| Package source: | InfiniumPurify_1.3.1.tar.gz |
| Windows binaries: | r-devel: InfiniumPurify_1.3.1.zip, r-release: InfiniumPurify_1.3.1.zip, r-oldrel: InfiniumPurify_1.3.1.zip |
| macOS binaries: | r-release (arm64): InfiniumPurify_1.3.1.tgz, r-oldrel (arm64): InfiniumPurify_1.3.1.tgz, r-release (x86_64): InfiniumPurify_1.3.1.tgz, r-oldrel (x86_64): InfiniumPurify_1.3.1.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.