The hardware and bandwidth for this mirror is donated by METANET, the Webhosting and Full Service-Cloud Provider.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]metanet.ch.

LTFHPlus: Implementation of LT-FH++

Implementation of LT-FH++, an extension of the liability threshold family history (LT-FH) model. LT-FH++ uses a Gibbs sampler for sampling from the truncated multivariate normal distribution and allows for flexible family structures. LT-FH++ was first described in Pedersen, Emil M., et al. (2022) <https://pure.au.dk/ws/portalfiles/portal/353346245/> as an extension to LT-FH with more flexible family structures, and again as the age-dependent liability threshold (ADuLT) model Pedersen, Emil M., et al. (2023) <https://www.nature.com/articles/s41467-023-41210-z> as an alternative to traditional time-to-event genome-wide association studies, where family history was not considered.

Version: 2.1.1
Imports: batchmeans, dplyr, future.apply, future, purrr, Rcpp, rlang, stats, stringr, tibble, tmvtnorm, tidyselect, igraph, xgboost, tidyr
LinkingTo: Rcpp
Suggests: MASS, knitr, rmarkdown, testthat
Published: 2024-02-12
DOI: 10.32614/CRAN.package.LTFHPlus
Author: Emil Michael Pedersen [aut, cre], Florian Privé [aut, ths], Bjarni Jóhann Vilhjálmsson [ths], Esben Agerbo [ths], Jette Steinbach [aut], Lucas Rasmussen [ctb]
Maintainer: Emil Michael Pedersen <emp at ph.au.dk>
BugReports: https://github.com/EmilMiP/LTFHPlus/issues
License: GPL-3
URL: https://github.com/EmilMiP/LTFHPlus
NeedsCompilation: yes
Language: "en-GB"
Materials: README NEWS
CRAN checks: LTFHPlus results

Documentation:

Reference manual: LTFHPlus.pdf

Downloads:

Package source: LTFHPlus_2.1.1.tar.gz
Windows binaries: r-devel: LTFHPlus_2.1.1.zip, r-release: LTFHPlus_2.1.1.zip, r-oldrel: LTFHPlus_2.1.1.zip
macOS binaries: r-release (arm64): LTFHPlus_2.1.1.tgz, r-oldrel (arm64): LTFHPlus_2.1.1.tgz, r-release (x86_64): LTFHPlus_2.1.1.tgz, r-oldrel (x86_64): LTFHPlus_2.1.1.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=LTFHPlus to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.