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Implements novel nonparametric approaches to address biases and confounding when comparing treatments or exposures in observational studies of outcomes. While designed and appropriate for use in studies involving medicine and the life sciences, the package can be used in other situations involving outcomes with multiple confounders. The package implements a family of methods for non-parametric bias correction when comparing treatments in observational studies, including survival analysis settings, where competing risks and/or censoring may be present. The approach extends to bias-corrected personalized predictions of treatment outcome differences, and analysis of heterogeneity of treatment effect-sizes across patient subgroups. For further details, please see: Lauve NR, Nelson SJ, Young SS, Obenchain RL, Lambert CG. LocalControl: An R Package for Comparative Safety and Effectiveness Research. Journal of Statistical Software. 2020. p. 1–32. Available from <doi:10.18637/jss.v096.i04>.
Version: | 1.1.4 |
Depends: | R (≥ 3.0.0) |
Imports: | Rcpp, gss, cluster, lattice, stats, graphics |
LinkingTo: | Rcpp |
Suggests: | colorspace, RColorBrewer, data.table, ggplot2, gridExtra, rpart, rpart.plot, xtable, knitr |
Published: | 2024-09-04 |
DOI: | 10.32614/CRAN.package.LocalControl |
Author: | Nicolas R. Lauve [aut], Stuart J. Nelson [aut], S. Stanley Young [aut], Robert L. Obenchain [aut], Melania Pintilie [ctb], Martin Kutz [ctb], Christophe G. Lambert [aut, cre] |
Maintainer: | Christophe G. Lambert <cglambert at salud.unm.edu> |
BugReports: | https://github.com/OHDSI/LocalControl/issues |
License: | Apache License 2.0 | file LICENSE |
URL: | https://github.com/OHDSI/LocalControl |
NeedsCompilation: | yes |
Citation: | LocalControl citation info |
Materials: | README NEWS |
CRAN checks: | LocalControl results |
Reference manual: | LocalControl.pdf |
Vignettes: |
LocalControl-jss-2020 (source, R code) |
Package source: | LocalControl_1.1.4.tar.gz |
Windows binaries: | r-devel: LocalControl_1.1.4.zip, r-release: LocalControl_1.1.4.zip, r-oldrel: LocalControl_1.1.4.zip |
macOS binaries: | r-release (arm64): LocalControl_1.1.4.tgz, r-oldrel (arm64): LocalControl_1.1.4.tgz, r-release (x86_64): LocalControl_1.1.4.tgz, r-oldrel (x86_64): LocalControl_1.1.4.tgz |
Old sources: | LocalControl archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.