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MAP: Multimodal Automated Phenotyping

Electronic health records (EHR) linked with biorepositories are a powerful platform for translational studies. A major bottleneck exists in the ability to phenotype patients accurately and efficiently. Towards that end, we developed an automated high-throughput phenotyping method integrating International Classification of Diseases (ICD) codes and narrative data extracted using natural language processing (NLP). Specifically, our proposed method, called MAP (Map Automated Phenotyping algorithm), fits an ensemble of latent mixture models on aggregated ICD and NLP counts along with healthcare utilization. The MAP algorithm yields a predicted probability of phenotype for each patient and a threshold for classifying subjects with phenotype yes/no (See Katherine P. Liao, et al. (2019) <doi:10.1101/587436>.).

Version: 0.1.3
Depends: R (≥ 3.4.0), flexmix (≥ 2.3-14), Matrix (≥ 1.2-10)
Suggests: knitr, rmarkdown
Published: 2019-04-01
DOI: 10.32614/CRAN.package.MAP
Author: Jiehuan Sun [aut, cre], Katherine P. Liao[aut], Sheng Yu [aut], Tianxi Cai [aut]
Maintainer: Jiehuan Sun <jiehuan.sun at gmail.com>
License: GPL-2
NeedsCompilation: no
CRAN checks: MAP results

Documentation:

Reference manual: MAP.pdf

Downloads:

Package source: MAP_0.1.3.tar.gz
Windows binaries: r-devel: MAP_0.1.3.zip, r-release: MAP_0.1.3.zip, r-oldrel: MAP_0.1.3.zip
macOS binaries: r-release (arm64): MAP_0.1.3.tgz, r-oldrel (arm64): MAP_0.1.3.tgz, r-release (x86_64): MAP_0.1.3.tgz, r-oldrel (x86_64): MAP_0.1.3.tgz

Reverse dependencies:

Reverse imports: sureLDA

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.