MyoScore: Transcriptomic Scoring for Human Skeletal Muscle Health

Calculate MyoScore, a genetically informed muscle health score, from bulk RNA sequencing (RNA-seq) raw count data. MyoScore integrates results from genome-wide association studies (GWAS) and transcriptome-wide association studies (TWAS) across 28 muscle-related phenotypes to quantify muscle health along five dimensions (Strength, Mass, LeanMuscle, Youth, Resilience), each scored from 0 to 100. The package provides preprocessing via counts per million (CPM) normalization, dimension-level and composite scoring, and visualization utilities including radar charts and grouped boxplots. For more information, see <https://github.com/Hirriririir/MyoScore>.

Version:	1.0.1
Depends:	R (≥ 4.0.0)
Imports:	stats, utils, graphics, grDevices
Suggests:	ggplot2 (≥ 3.4.0), fmsb, patchwork, testthat (≥ 3.0.0), knitr, rmarkdown
Published:	2026-04-02
DOI:	10.32614/CRAN.package.MyoScore
Author:	Huahua Zhong [aut, cre]
Maintainer:	Huahua Zhong <huahuazhong at fudan.edu.cn>
BugReports:	https://github.com/Hirriririir/MyoScore/issues
License:	MIT + file LICENSE
URL:	https://github.com/Hirriririir/MyoScore
NeedsCompilation:	no
Materials:	README
CRAN checks:	MyoScore results

Documentation:

Reference manual:	MyoScore.html , MyoScore.pdf
Vignettes:	Quick Start: MyoScore (source, R code)

Downloads:

Package source:	MyoScore_1.0.1.tar.gz
Windows binaries:	r-devel: MyoScore_1.0.1.zip, r-release: not available, r-oldrel: not available
macOS binaries:	r-release (arm64): MyoScore_1.0.1.tgz, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available

Linking:

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