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A system for fast, accurate, and flexible whole genome bisulfite sequencing (WGBS) data analysis of two-condition comparisons. Principal Component BiSulfite, 'PCBS', assigns methylated loci eigenvector values from the treatment-delineating principal component in lieu of running millions of pairwise statistical tests, which dramatically increases analysis flexibility and reduces computational requirements. Methods: <https://katlande.github.io/PCBS/articles/Differential_Methylation.html>.
| Version: | 0.1.1 |
| Depends: | R (≥ 2.10) |
| Imports: | ggplot2, tibble, ggrepel, dplyr, data.table |
| Published: | 2024-08-27 |
| DOI: | 10.32614/CRAN.package.PCBS |
| Author: | Kathryn Lande [aut, cre, cph] |
| Maintainer: | Kathryn Lande <kathryn.lande at mail.mcgill.ca> |
| BugReports: | https://github.com/katlande/PCBS/issues |
| License: | GPL-3 |
| URL: | https://github.com/katlande/PCBS |
| NeedsCompilation: | no |
| CRAN checks: | PCBS results |
| Reference manual: | PCBS.pdf |
| Package source: | PCBS_0.1.1.tar.gz |
| Windows binaries: | r-devel: PCBS_0.1.1.zip, r-release: PCBS_0.1.1.zip, r-oldrel: PCBS_0.1.1.zip |
| macOS binaries: | r-release (arm64): PCBS_0.1.1.tgz, r-oldrel (arm64): PCBS_0.1.1.tgz, r-release (x86_64): PCBS_0.1.1.tgz, r-oldrel (x86_64): PCBS_0.1.1.tgz |
| Old sources: | PCBS archive |
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These binaries (installable software) and packages are in development.
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