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SCORPION: Single Cell Oriented Reconstruction of PANDA Individual Optimized Networks

Constructs cell-type–specific gene regulatory networks from single-cell RNA-sequencing data. The method implements the SCORPION algorithm, which first aggregates individual cells into supercells and then applies PANDA (Passing Attributes between Networks for Data Assimilation) to infer transcription factor–target regulatory relationships. It also provides statistical methods for differential edge analysis.

Version: 1.3.1
Depends: R (≥ 3.5.0)
Imports: cli, methods, irlba, igraph, RANN, Matrix, pbapply, dplyr
Suggests: RhpcBLASctl, testthat
Published: 2026-02-12
DOI: 10.32614/CRAN.package.SCORPION
Author: Daniel Osorio ORCID iD [aut, cre], Marieke L. Kuijjer ORCID iD [aut]
Maintainer: Daniel Osorio <daniecos at uio.no>
BugReports: https://github.com/kuijjerlab/SCORPION/issues
License: GPL-3
URL: https://github.com/kuijjerlab/SCORPION
NeedsCompilation: no
CRAN checks: SCORPION results

Documentation:

Reference manual: SCORPION.html , SCORPION.pdf

Downloads:

Package source: SCORPION_1.3.1.tar.gz
Windows binaries: r-devel: SCORPION_1.3.1.zip, r-release: SCORPION_1.3.1.zip, r-oldrel: SCORPION_1.3.1.zip
macOS binaries: r-release (arm64): SCORPION_1.3.1.tgz, r-oldrel (arm64): SCORPION_1.3.1.tgz, r-release (x86_64): SCORPION_1.3.1.tgz, r-oldrel (x86_64): SCORPION_1.3.1.tgz
Old sources: SCORPION archive

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.