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SmartPK: Automated Noncompartmental Pharmacokinetic Analysis

Provides functions for automated noncompartmental pharmacokinetic (NCA) analysis using concentration-time data. The package estimates pharmacokinetic parameters including area under the concentration-time curve (AUC), area under the first moment curve (AUMC), maximum concentration (Cmax), time to maximum concentration (Tmax), terminal elimination rate constant (Kel), elimination half-life, clearance, volume of distribution, and mean residence time (MRT). It supports automatic terminal phase selection, bootstrap confidence intervals, and publication-ready concentration-time profiles. Methods are based on Gibaldi and Perrier (1982, ISBN:9780824710422).

Version: 0.1.0
Imports: ggplot2, rlang
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2026-08-24
DOI: 10.32614/CRAN.package.SmartPK (may not be active yet)
Author: N. Shreenithi [aut, cre], S. Vishnu Shankar [aut], Balaji Kannan [aut]
Maintainer: N. Shreenithi <Shreenithi092 at gmail.com>
License: GPL-3
NeedsCompilation: no
CRAN checks: SmartPK results

Documentation:

Reference manual: SmartPK.html , SmartPK.pdf

Downloads:

Package source: SmartPK_0.1.0.tar.gz
Windows binaries: r-devel: SmartPK_0.1.0.zip, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): SmartPK_0.1.0.tgz, r-oldrel (arm64): SmartPK_0.1.0.tgz, r-release (x86_64): SmartPK_0.1.0.tgz, r-oldrel (x86_64): SmartPK_0.1.0.tgz

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.