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UnplanSimon: Methods for Managing Enrollment Deviation in Simon's Two-Stage Design

Methods for managing under- and over-enrollment in Simon's Two-Stage Design are offered by providing adaptive threshold adjustments and sample size recalibration. It also includes post-inference analysis tools to support clinical trial design and evaluation. The package is designed to enhance flexibility and accuracy in trial design, ensuring better outcomes in oncology and other clinical studies. Yunhe Liu, Haitao Pan (2024). Submitted.

Version: 0.1.0
Depends: R (≥ 3.5.0)
Imports: stats
Suggests: knitr, rmarkdown, clinfun (≥ 3.0.0)
Published: 2024-10-25
DOI: 10.32614/CRAN.package.UnplanSimon
Author: Yunhe Liu [aut, cre], Haitao Pan [aut]
Maintainer: Yunhe Liu <yunhe.liu at tamu.edu>
License: GPL (≥ 3)
NeedsCompilation: no
Materials: NEWS
CRAN checks: UnplanSimon results

Documentation:

Reference manual: UnplanSimon.pdf
Vignettes: UnplanSimon (source, R code)

Downloads:

Package source: UnplanSimon_0.1.0.tar.gz
Windows binaries: r-devel: UnplanSimon_0.1.0.zip, r-release: UnplanSimon_0.1.0.zip, r-oldrel: UnplanSimon_0.1.0.zip
macOS binaries: r-release (arm64): UnplanSimon_0.1.0.tgz, r-oldrel (arm64): UnplanSimon_0.1.0.tgz, r-release (x86_64): UnplanSimon_0.1.0.tgz, r-oldrel (x86_64): UnplanSimon_0.1.0.tgz

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.