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Contains functions carrying out adaptive procedures using mixed scaling approach to establish bioequivalence for in-vitro permeation test (IVPT) data. Currently, the package provides procedures based on parallel replicate design and balanced data, according to the U.S. Food and Drug Administration's "Draft Guidance on Acyclovir" <https://www.accessdata.fda.gov/drugsatfda_docs/psg/Acyclovir_topical%20cream_RLD%2021478_RV12-16.pdf>. Potvin et al. (2008) <doi:10.1002/pst.294> provides the basis for our adaptive design (see Method B). For a comprehensive overview of the method, refer to Lim et al. (2023) <doi:10.1002/pst.2333>. This package reflects the views of the authors and should not be construed to represent the views or policies of the U.S. Food and Drug Administration.
| Version: | 1.1.0 |
| Depends: | R (≥ 3.4) |
| Imports: | Rcpp, rgl |
| LinkingTo: | Rcpp, RcppArmadillo, RcppProgress |
| Suggests: | knitr, rmarkdown |
| Published: | 2024-01-26 |
| DOI: | 10.32614/CRAN.package.adaptIVPT |
| Author: | Daeyoung Lim [aut, cre], Elena Rantou [ctb], Jessica Kim [ctb], Sungwoo Choi [ctb], Nam Hee Choi [ctb], Stella Grosser [ctb] |
| Maintainer: | Daeyoung Lim <Daeyoung.Lim at fda.hhs.gov> |
| License: | GPL (≥ 3) |
| NeedsCompilation: | yes |
| Citation: | adaptIVPT citation info |
| Materials: | NEWS |
| CRAN checks: | adaptIVPT results |
| Reference manual: | adaptIVPT.pdf |
| Package source: | adaptIVPT_1.1.0.tar.gz |
| Windows binaries: | r-devel: adaptIVPT_1.1.0.zip, r-release: adaptIVPT_1.1.0.zip, r-oldrel: adaptIVPT_1.1.0.zip |
| macOS binaries: | r-release (arm64): adaptIVPT_1.1.0.tgz, r-oldrel (arm64): adaptIVPT_1.1.0.tgz, r-release (x86_64): adaptIVPT_1.1.0.tgz, r-oldrel (x86_64): adaptIVPT_1.1.0.tgz |
| Old sources: | adaptIVPT archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.