bfbin2arm: Bayes Factor Design for Two-Arm Binomial Trials

Design and analysis of one- and two-stage clinical trials using Bayes factors. Implements methods for binomial and continuous endpoints, including point-null and directional hypotheses, power calculations, and sample size calibration. Supports one-arm trials with a single treatment arm and two-arm trials with treatment and control arms. Includes methods for equivalence, non-inferiority, and superiority designs.

Version:	0.1.7
Depends:	R (≥ 4.0.0)
Imports:	stats, statmod, VGAM, dplyr, parallel, utils, ggplot2, patchwork, rlang, gridExtra
Suggests:	knitr, rmarkdown, kableExtra, testthat (≥ 3.0.0), purrr, tidyr
Published:	2026-10-28
DOI:	10.32614/CRAN.package.bfbin2arm
Author:	Riko Kelter [aut, cre]
Maintainer:	Riko Kelter <rkelter at uni-koeln.de>
License:	GPL-3
URL:	https://rikokelter.github.io/bfbin2arm/, https://arxiv.org/abs/2511.23144, https://arxiv.org/abs/2603.01715, https://arxiv.org/abs/2502.02914, https://arxiv.org/abs/2606.02410
NeedsCompilation:	no
CRAN checks:	bfbin2arm results

Documentation:

Reference manual:

bfbin2arm.html , bfbin2arm.pdf

Vignettes:

Calibrated Bayesian One-Sample and Paired t-Tests for Continuous Endpoints in Clinical Trials (source, R code) Clinical trial designs in bfbin2arm (source, R code) Calibration of Bayesian one-stage designs for single-arm phase II trials with binary endpoints (source, R code) Optimal Bayesian calibration for single-arm two-stage Bayes factor designs (source, R code) Optimal frequentist calibration for single-arm two-stage Bayes factor designs with binary endpoints (source, R code) Optimal full calibration for single-arm two-stage Bayes factor designs with binary endpoints (source, R code) Optimal hybrid calibration for single-arm two-stage Bayes factor designs with binary endpoints (source, R code) Optimal Bayesian calibration of two-arm two-stage Bayes factor designs with binary endpoints (source, R code) Bayesian calibration of two-arm one-stage Bayes factor designs with binary endpoints (source, R code)

Downloads:

Package source:	bfbin2arm_0.1.7.tar.gz
Windows binaries:	r-devel: bfbin2arm_0.1.6.zip, r-release: bfbin2arm_0.1.6.zip, r-oldrel: bfbin2arm_0.1.6.zip
macOS binaries:	r-release (arm64): bfbin2arm_0.1.6.tgz, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): bfbin2arm_0.1.6.tgz
Old sources:	bfbin2arm archive

Linking:

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