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Implements functions to update Bayesian Predictive Power Computations after not stopping a clinical trial at an interim analysis. Such an interim analysis can either be blinded or unblinded. Code is provided for Normally distributed endpoints with known variance, with a prominent example being the hazard ratio.
| Version: | 1.0.4 |
| Depends: | mvtnorm, R (≥ 2.10) |
| Suggests: | knitr, rmarkdown |
| Published: | 2022-01-13 |
| Author: | Kaspar Rufibach, Paul Jordan, Markus Abt |
| Maintainer: | Kaspar Rufibach <kaspar.rufibach at roche.com> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| Materials: | NEWS |
| CRAN checks: | bpp results |
| Reference manual: | bpp.pdf |
| Vignettes: |
Sequentially updating the likelihood of success of a Phase 3 pivotal time-to-event trial based on interim analyses or external information |
| Package source: | bpp_1.0.4.tar.gz |
| Windows binaries: | r-devel: bpp_1.0.4.zip, r-release: bpp_1.0.4.zip, r-oldrel: bpp_1.0.4.zip |
| macOS binaries: | r-release (arm64): bpp_1.0.4.tgz, r-oldrel (arm64): bpp_1.0.4.tgz, r-release (x86_64): bpp_1.0.4.tgz, r-oldrel (x86_64): bpp_1.0.4.tgz |
| Old sources: | bpp archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.