The hardware and bandwidth for this mirror is donated by METANET, the Webhosting and Full Service-Cloud Provider.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]metanet.ch.
Designs guide sequences for CRISPR/Cas9 genome editing and provides information on sequence features pertinent to guide efficiency. Sequence features include annotated off-target predictions in a user-selected genome and a predicted efficiency score based on the model described in Doench et al. (2016) <doi:10.1038/nbt.3437>. Users are able to import additional genomes and genome annotation files to use when searching and annotating off-target hits. All guide sequences and off-target data can be generated through the 'R' console with sgRNA_Design() or through 'crispRdesignR's' user interface with crispRdesignRUI(). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and the associated protein Cas9 refer to a technique used in genome editing.
| Version: | 1.1.7 |
| Depends: | R (≥ 2.10) |
| Imports: | Biostrings, gbm, GenomicRanges, BiocGenerics, IRanges, GenomeInfoDb, S4Vectors, rtracklayer, stringr, vtreat, shiny, DT |
| Suggests: | BSgenome.Scerevisiae.UCSC.sacCer3 |
| Published: | 2023-04-12 |
| DOI: | 10.32614/CRAN.package.crispRdesignR |
| Author: | Dylan Beeber [aut, cre], Frederic Chain [aut] |
| Maintainer: | Dylan Beeber <dylan.beeber at gmail.com> |
| License: | GPL-3 |
| URL: | <https://github.com/dylanbeeber/crispRdesignR> |
| NeedsCompilation: | no |
| Materials: | README |
| CRAN checks: | crispRdesignR results |
| Reference manual: | crispRdesignR.pdf |
| Package source: | crispRdesignR_1.1.7.tar.gz |
| Windows binaries: | r-devel: crispRdesignR_1.1.7.zip, r-release: crispRdesignR_1.1.7.zip, r-oldrel: crispRdesignR_1.1.7.zip |
| macOS binaries: | r-release (arm64): crispRdesignR_1.1.7.tgz, r-oldrel (arm64): crispRdesignR_1.1.7.tgz, r-release (x86_64): crispRdesignR_1.1.7.tgz, r-oldrel (x86_64): crispRdesignR_1.1.7.tgz |
| Old sources: | crispRdesignR archive |
Please use the canonical form https://CRAN.R-project.org/package=crispRdesignR to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.