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Pooling estimates reported in meta-analyses (literature-based, LB) and estimates based on individual participant data (IPD) is not straight-forward as the details of the LB nonlinear function estimate are not usually reported. This package pools the nonlinear IPD dose-response estimates based on a natural cubic spline from lm or glm with the pointwise LB estimates and their estimated variances. Details will be presented in Härkänen, Tapanainen, Sares-Jäske, Männistö, Kaartinen and Paalanen (2025) "Novel pooling method for nonlinear cohort analysis and meta-analysis estimates: Predicting health outcomes based on climate-friendly diets" (under revision) <https://journals.lww.com/epidem/pages/default.aspx>.
| Version: | 0.1.0 |
| Depends: | R (≥ 4.2.0) |
| Imports: | rlang, dplyr, tidyr, tibble, stringr, meta, optimization |
| Suggests: | knitr, rmarkdown, splines2 |
| Published: | 2025-07-21 |
| DOI: | 10.32614/CRAN.package.metasplines |
| Author: | Tommi Härkänen [aut, cre] |
| Maintainer: | Tommi Härkänen <tommi.harkanen at thl.fi> |
| License: | GPL (≥ 3) |
| NeedsCompilation: | no |
| Citation: | metasplines citation info |
| Materials: | README |
| CRAN checks: | metasplines results |
| Reference manual: | metasplines.html , metasplines.pdf |
| Vignettes: |
Introduction (source, R code) |
| Package source: | metasplines_0.1.0.tar.gz |
| Windows binaries: | r-devel: metasplines_0.1.0.zip, r-release: not available, r-oldrel: not available |
| macOS binaries: | r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): metasplines_0.1.0.tgz, r-oldrel (x86_64): metasplines_0.1.0.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.