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Software to aid in modeling and analyzing mass-spectrometry-based proteome melting data. Quantitative data is imported and normalized and thermal behavior is modeled at the protein level. Methods exist for normalization, modeling, visualization, and export of results. For a general introduction to MS-based thermal profiling, see Savitski et al. (2014) <doi:10.1126/science.1255784>.
Version: | 0.4.7 |
Imports: | foreach, parallel, doParallel, nls2, RColorBrewer, plotrix |
Suggests: | RSQLite, testthat, knitr, rmarkdown |
Published: | 2017-04-27 |
DOI: | 10.32614/CRAN.package.mstherm |
Author: | Jeremy Volkening [aut, cre] |
Maintainer: | Jeremy Volkening <jdv at base2bio.com> |
License: | GPL-3 |
NeedsCompilation: | no |
Materials: | README NEWS |
CRAN checks: | mstherm results |
Reference manual: | mstherm.pdf |
Vignettes: |
Thermal proteome profiling with MSTherm |
Package source: | mstherm_0.4.7.tar.gz |
Windows binaries: | r-devel: mstherm_0.4.7.zip, r-release: mstherm_0.4.7.zip, r-oldrel: mstherm_0.4.7.zip |
macOS binaries: | r-release (arm64): mstherm_0.4.7.tgz, r-oldrel (arm64): mstherm_0.4.7.tgz, r-release (x86_64): mstherm_0.4.7.tgz, r-oldrel (x86_64): mstherm_0.4.7.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.