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Design and analysis of confirmatory adaptive clinical trials using the optimal conditional error framework according to Brannath and Bauer (2004) <doi:10.1111/j.0006-341X.2004.00221.x>. An extension to the optimal conditional error function using interim estimates as described in Brannath and Dreher (2024) <doi:10.48550/arXiv.2402.00814> and functions to ensure that the resulting conditional error function is non-increasing are also available.
Version: | 1.0.0 |
Imports: | ggplot2, methods |
Suggests: | knitr, rmarkdown, testthat (≥ 3.0.0) |
Published: | 2025-09-09 |
DOI: | 10.32614/CRAN.package.optconerrf |
Author: | Morten Dreher [aut, cre],
Werner Brannath |
Maintainer: | Morten Dreher <morten.dreher at outlook.de> |
BugReports: | https://github.com/morten-dreher/optconerrf/issues |
License: | GPL (≥ 3) |
URL: | https://github.com/morten-dreher/optconerrf |
NeedsCompilation: | no |
Materials: | README, NEWS |
CRAN checks: | optconerrf results |
Reference manual: | optconerrf.html , optconerrf.pdf |
Vignettes: |
Using Constraints and Interim Estimates for the Optimal Conditional Error Function (source, R code) introduction (source, R code) |
Package source: | optconerrf_1.0.0.tar.gz |
Windows binaries: | r-devel: not available, r-release: not available, r-oldrel: not available |
macOS binaries: | r-release (arm64): optconerrf_1.0.0.tgz, r-oldrel (arm64): optconerrf_1.0.0.tgz, r-release (x86_64): optconerrf_1.0.0.tgz, r-oldrel (x86_64): optconerrf_1.0.0.tgz |
Please use the canonical form https://CRAN.R-project.org/package=optconerrf to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.