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priorityelasticnet: Comprehensive Analysis of Multi-Omics Data Using an Offset-Based Method

Priority-ElasticNet extends the Priority-LASSO method (Klau et al. (2018) <doi:10.1186/s12859-018-2344-6>) by incorporating the ElasticNet penalty, allowing for both L1 and L2 regularization. This approach fits successive ElasticNet models for several blocks of (omics) data with different priorities, using the predicted values from each block as an offset for the subsequent block. It also offers robust options to handle block-wise missingness in multi-omics data, improving the flexibility and applicability of the model in the presence of incomplete datasets.

Version: 0.1.0
Depends: R (≥ 3.5.0)
Imports: survival, glmnet, utils, checkmate, shiny, tidyr, dplyr, caret, pROC, PRROC, plotrix, ggplot2, magrittr, tibble, broom, cvms
Suggests: ipflasso, rlang, knitr, rmarkdown, glmSparseNet
Published: 2025-01-13
DOI: 10.32614/CRAN.package.priorityelasticnet
Author: Laila Qadir Musib [aut, cre], Eunice Carrasquinha [aut], Helena Mouriño [aut]
Maintainer: Laila Qadir Musib <statleila98 at gmail.com>
License: GPL-3
NeedsCompilation: no
CRAN checks: priorityelasticnet results [issues need fixing before 2025-01-28]

Documentation:

Reference manual: priorityelasticnet.pdf
Vignettes: Comprehensive Analysis of Multi-Omics Data Using elastic net based on priorities (source, R code)

Downloads:

Package source: priorityelasticnet_0.1.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: priorityelasticnet_0.1.0.zip
macOS binaries: r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.