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Computes noncompartmental pharmacokinetic parameters for drug concentration profiles. For each profile, data imputations and adjustments are made as necessary and basic parameters are estimated. Supports single dose, multi-dose, and multi-subject data. Supports steady-state calculations and various routes of drug administration. See ?qpNCA and vignettes. Methodology follows Rowland and Tozer (2011, ISBN:978-0-683-07404-8), Gabrielsson and Weiner (1997, ISBN:978-91-9765-100-4), and Gibaldi and Perrier (1982, ISBN:978-0824710422).
Version: | 1.1.6 |
Depends: | R (≥ 3.3.0) |
Imports: | dplyr (≥ 0.7.0), tidyr (≥ 0.8.2), magrittr, ggplot2, knitr |
Suggests: | rmarkdown, markdown, covr, testthat (≥ 2.1.0) |
Published: | 2021-08-16 |
DOI: | 10.32614/CRAN.package.qpNCA |
Author: | Jan Huisman [aut, cre], Koen Jolling [ctb], Krina Mehta [ctb], Tim Bergsma [ctb] |
Maintainer: | Jan Huisman <jan.huisman at qpharmetra.com> |
License: | GPL-3 |
NeedsCompilation: | no |
Materials: | README |
In views: | MissingData, Pharmacokinetics |
CRAN checks: | qpNCA results |
Reference manual: | qpNCA.pdf |
Vignettes: |
Parameter Guidelines A User Guide for qpNCA Example Full NCA Analysis Example Stepwise NCA Analysis |
Package source: | qpNCA_1.1.6.tar.gz |
Windows binaries: | r-devel: qpNCA_1.1.6.zip, r-release: qpNCA_1.1.6.zip, r-oldrel: qpNCA_1.1.6.zip |
macOS binaries: | r-release (arm64): qpNCA_1.1.6.tgz, r-oldrel (arm64): qpNCA_1.1.6.tgz, r-release (x86_64): qpNCA_1.1.6.tgz, r-oldrel (x86_64): qpNCA_1.1.6.tgz |
Old sources: | qpNCA archive |
Please use the canonical form https://CRAN.R-project.org/package=qpNCA to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.