seroreconstruct: Reconstructing Antibody Dynamics to Estimate the Risk of Influenza Virus Infection
A Bayesian framework for inferring influenza infection status from serial antibody measurements. Jointly estimates season-specific infection probabilities, antibody boosting and waning after infection, and baseline hemagglutination inhibition (HAI) titer distributions via Markov chain Monte Carlo (MCMC). Supports multi-season analysis and subgroup comparisons via a group_by interface. See Tsang et al. (2022) <doi:10.1038/s41467-022-29310-8> for methodological details.
| Version: | 1.1.5 |
| Depends: | R (≥ 3.5.0) |
| Imports: | Rcpp (≥ 1.0.9), RcppParallel |
| LinkingTo: | Rcpp, RcppArmadillo, RcppParallel |
| Suggests: | testthat (≥ 3.0.0), knitr, rmarkdown |
| Published: | 2026-04-03 |
| DOI: | 10.32614/CRAN.package.seroreconstruct |
| Author: | Tim Tsang  [aut,
cre] |
| Maintainer: | Tim Tsang <timkltsang at gmail.com> |
| BugReports: | https://github.com/timktsang/seroreconstruct/issues |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| URL: | https://github.com/timktsang/seroreconstruct |
| NeedsCompilation: | yes |
| SystemRequirements: | TBB |
| Citation: | seroreconstruct citation info |
| Materials: | README, NEWS |
| CRAN checks: | seroreconstruct results |
Documentation:
| Reference manual: | seroreconstruct.html , seroreconstruct.pdf |
| Vignettes: |
Getting Started with seroreconstruct (source, R code) Statistical Methodology (source, R code) |
Downloads:
| Package source: | seroreconstruct_1.1.5.tar.gz |
| Windows binaries: | r-devel: seroreconstruct_1.1.5.zip, r-release: not available, r-oldrel: not available |
| macOS binaries: | r-release (arm64): seroreconstruct_1.1.5.tgz, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available |
Linking:
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