The hardware and bandwidth for this mirror is donated by METANET, the Webhosting and Full Service-Cloud Provider.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]metanet.ch.
Many complex diseases are known to be affected by the interactions between genetic variants and environmental exposures beyond the main genetic and environmental effects. Existing Bayesian methods for gene-environment (G×E) interaction studies are challenged by the high-dimensional nature of the study and the complexity of environmental influences. We have developed a novel and powerful semi-parametric Bayesian variable selection method that can accommodate linear and nonlinear G×E interactions simultaneously (Ren et al. (2020) <doi:10.1002/sim.8434>). Furthermore, the proposed method can conduct structural identification by distinguishing nonlinear interactions from main effects only case within Bayesian framework. Spike-and-slab priors are incorporated on both individual and group level to shrink coefficients corresponding to irrelevant main and interaction effects to zero exactly. The Markov chain Monte Carlo algorithms of the proposed and alternative methods are efficiently implemented in C++.
Version: | 0.2.1 |
Depends: | R (≥ 4.0.0) |
Imports: | Rcpp, splines, glmnet, utils, stats, ggplot2 |
LinkingTo: | Rcpp, RcppArmadillo, testthat |
Suggests: | testthat (≥ 3.0.0), covr |
Published: | 2024-03-12 |
DOI: | 10.32614/CRAN.package.spinBayes |
Author: | Jie Ren, Fei Zhou, Xiaoxi Li, Cen Wu, Yu Jiang |
Maintainer: | Jie Ren <jieren at ksu.edu> |
BugReports: | https://github.com/jrhub/spinBayes/issues |
License: | GPL-2 |
URL: | https://github.com/jrhub/spinBayes |
NeedsCompilation: | yes |
Materials: | README |
CRAN checks: | spinBayes results |
Reference manual: | spinBayes.pdf |
Package source: | spinBayes_0.2.1.tar.gz |
Windows binaries: | r-devel: spinBayes_0.2.1.zip, r-release: spinBayes_0.2.1.zip, r-oldrel: spinBayes_0.2.1.zip |
macOS binaries: | r-release (arm64): spinBayes_0.2.1.tgz, r-oldrel (arm64): spinBayes_0.2.1.tgz, r-release (x86_64): spinBayes_0.2.1.tgz, r-oldrel (x86_64): spinBayes_0.2.1.tgz |
Old sources: | spinBayes archive |
Please use the canonical form https://CRAN.R-project.org/package=spinBayes to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.