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sssc: Same Species Sample Contamination Detection

Imports Variant Calling Format file into R. It can detect whether a sample contains contaminant from the same species. In the first stage of the approach, a change-point detection method is used to identify copy number variations for filtering. Next, features are extracted from the data for a support vector machine model. For log-likelihood calculation, the deviation parameter is estimated by maximum likelihood method. Using a radial basis function kernel support vector machine, the contamination of a sample can be detected.

Version: 1.0.0
Depends: R (≥ 3.4.0)
Imports: changepoint, e1071, ggplot2, stats, VGAM
Published: 2018-06-15
DOI: 10.32614/CRAN.package.sssc
Author: Tao Jiang [aut, cre]
Maintainer: Tao Jiang <tjiang8 at ncsu.edu>
License: GPL-2
NeedsCompilation: no
Materials: README
CRAN checks: sssc results

Documentation:

Reference manual: sssc.pdf

Downloads:

Package source: sssc_1.0.0.tar.gz
Windows binaries: r-devel: sssc_1.0.0.zip, r-release: sssc_1.0.0.zip, r-oldrel: sssc_1.0.0.zip
macOS binaries: r-release (arm64): sssc_1.0.0.tgz, r-oldrel (arm64): sssc_1.0.0.tgz, r-release (x86_64): sssc_1.0.0.tgz, r-oldrel (x86_64): sssc_1.0.0.tgz

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.