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Up-and-Down (UD) is the most popular design approach for dose-finding, but it has been severely under-served by the statistical and computing communities. This is the first package that comprehensively addresses UD's needs. Recent applied UD tutorial: Oron et al., 2022 <doi:10.1097/ALN.0000000000004282>. Recent methodological overview: Oron and Flournoy, 2024 <doi:10.51387/24-NEJSDS74>.
| Version: | 0.3.0 |
| Imports: | cir, expm, MASS, plyr |
| Suggests: | knitr, rmarkdown |
| Published: | 2025-06-16 |
| DOI: | 10.32614/CRAN.package.upndown |
| Author: | Assaf P. Oron [cre, aut] |
| Maintainer: | Assaf P. Oron <assaf.oron at gmail.com> |
| License: | GPL-2 |
| NeedsCompilation: | no |
| CRAN checks: | upndown results |
| Reference manual: | upndown.pdf |
| Vignettes: |
'upndown' Package Vignette 1: Up-and-Down Basics (source, R code) |
| Package source: | upndown_0.3.0.tar.gz |
| Windows binaries: | r-devel: upndown_0.3.0.zip, r-release: upndown_0.3.0.zip, r-oldrel: upndown_0.3.0.zip |
| macOS binaries: | r-release (arm64): upndown_0.3.0.tgz, r-oldrel (arm64): upndown_0.3.0.tgz, r-release (x86_64): upndown_0.3.0.tgz, r-oldrel (x86_64): upndown_0.3.0.tgz |
| Old sources: | upndown archive |
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These binaries (installable software) and packages are in development.
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