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valytics: Statistical Methods for Analytical Method Comparison and Validation

Provides statistical methods for analytical method comparison and validation studies. Implements Bland-Altman analysis for assessing agreement between measurement methods (Bland & Altman (1986) <doi:10.1016/S0140-6736(86)90837-8>), Passing-Bablok regression for non-parametric method comparison (Passing & Bablok (1983) <doi:10.1515/cclm.1983.21.11.709>), and Deming regression accounting for measurement error in both variables (Linnet (1993) <doi:10.1093/clinchem/39.3.424>). Also includes tools for setting quality goals based on biological variation (Fraser & Petersen (1993) <doi:10.1093/clinchem/39.7.1447>) and calculating Six Sigma metrics. Commonly used in clinical laboratory method validation. Provides publication-ready plots and comprehensive statistical summaries.

Version: 0.3.0
Depends: R (≥ 3.5.0)
Imports: ggplot2, robslopes
Suggests: testthat (≥ 3.0.0), knitr (≥ 1.43), rmarkdown (≥ 2.22)
Published: 2026-01-22
DOI: 10.32614/CRAN.package.valytics
Author: Marcello Grassi ORCID iD [aut, cre]
Maintainer: Marcello Grassi <marcello.grassi at tum.de>
BugReports: https://github.com/marcellogr/valytics/issues
License: GPL-3
URL: https://github.com/marcellogr/valytics
NeedsCompilation: no
Materials: README, NEWS
CRAN checks: valytics results

Documentation:

Reference manual: valytics.html , valytics.pdf
Vignettes: Deming Regression for Method Comparison (source, R code)
Method Comparison Workflow (source, R code)
Setting Quality Goals with Biological Variation (source, R code)
Understanding Method Comparison Statistics (source, R code)

Downloads:

Package source: valytics_0.3.0.tar.gz
Windows binaries: r-devel: valytics_0.3.0.zip, r-release: valytics_0.3.0.zip, r-oldrel: valytics_0.3.0.zip
macOS binaries: r-release (arm64): valytics_0.3.0.tgz, r-oldrel (arm64): valytics_0.3.0.tgz, r-release (x86_64): valytics_0.3.0.tgz, r-oldrel (x86_64): valytics_0.3.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=valytics to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.