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xpose4: Diagnostics for Nonlinear Mixed-Effect Models

A model building aid for nonlinear mixed-effects (population) model analysis using NONMEM, facilitating data set checkout, exploration and visualization, model diagnostics, candidate covariate identification and model comparison. The methods are described in Keizer et al. (2013) <doi:10.1038/psp.2013.24>, and Jonsson et al. (1999) <doi:10.1016/s0169-2607(98)00067-4>.

Version: 4.7.3
Depends: R (≥ 2.2.0), lattice
Imports: Hmisc, survival, dplyr, tibble, methods, lazyeval, gam, splines, grid, readr
Suggests: testthat
Published: 2024-02-22
DOI: 10.32614/CRAN.package.xpose4
Author: Andrew C. Hooker [aut, cre, cph], Mats O. Karlsson [aut, cph], Justin J. Wilkins [aut], E. Niclas Jonsson [aut, trl, cph], Ron Keizer [ctb] (functionality for bootstrap of GAM and SCM)
Maintainer: Andrew C. Hooker <andrew.hooker at farmaci.uu.se>
BugReports: https://github.com/UUPharmacometrics/xpose4/issues
License: LGPL (≥ 3)
Copyright: 2009-2022 Andrew C. Hooker, E. Niclas Jonsson and Mats O. Karlsson. 2005-2008 Andrew C. Hooker, Justin J. Wilkins, Mats O. Karlsson and E. Niclas Jonsson. 1998-2004 E. Niclas Jonsson and Mats Karlsson.
URL: https://uupharmacometrics.github.io/xpose4/, https://github.com/UUPharmacometrics/xpose4
NeedsCompilation: no
Citation: xpose4 citation info
Materials: README NEWS
In views: Pharmacokinetics
CRAN checks: xpose4 results

Documentation:

Reference manual: xpose4.pdf

Downloads:

Package source: xpose4_4.7.3.tar.gz
Windows binaries: r-devel: xpose4_4.7.3.zip, r-release: xpose4_4.7.3.zip, r-oldrel: xpose4_4.7.3.zip
macOS binaries: r-release (arm64): xpose4_4.7.3.tgz, r-oldrel (arm64): xpose4_4.7.3.tgz, r-release (x86_64): xpose4_4.7.3.tgz, r-oldrel (x86_64): xpose4_4.7.3.tgz
Old sources: xpose4 archive

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.