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AHTauDesign: Prospective Trial Planning for Average Hazard Estimands

Provides a simulation-based prospective planning workflow for average hazard estimands in two-arm time-to-event trials. Supports calibration and freezing of design-specific information-support rules, assessment of clinically preferred truncation horizons, conditional selection of clinically acceptable alternative horizons, and reverse design over sample size and additional follow-up. Separates information support from statistical power and supports auditable planning reports.

Version: 1.0
Depends: R (≥ 4.1.0)
Imports: stats, survAH (≥ 1.2.0)
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0), roxygen2
Published: 2026-10-18
DOI: 10.32614/CRAN.package.AHTauDesign
Author: Xinyue Zhao [aut, cre], Haitao Pan [aut]
Maintainer: Xinyue Zhao <xinyuezhao27 at gwu.edu>
License: GPL-3
NeedsCompilation: no
Materials: README, NEWS
CRAN checks: AHTauDesign results

Documentation:

Reference manual: AHTauDesign.html , AHTauDesign.pdf
Vignettes: Getting Started with AHTauDesign (source, R code)

Downloads:

Package source: AHTauDesign_1.0.tar.gz
Windows binaries: r-devel: AHTauDesign_1.0.zip, r-release: AHTauDesign_1.0.zip, r-oldrel: AHTauDesign_1.0.zip
macOS binaries: r-release (arm64): AHTauDesign_1.0.tgz, r-oldrel (arm64): AHTauDesign_1.0.tgz, r-release (x86_64): AHTauDesign_1.0.tgz, r-oldrel (x86_64): AHTauDesign_1.0.tgz
Old sources: AHTauDesign archive

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.