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Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>, Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>, Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>, Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>, Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.
Version: | 6.0.3 |
Depends: | R (≥ 4.0.0) |
Imports: | inline, utils, methods, deSolve, Deriv, scales, devtools, ggplot2, Matrix, pracma, stringr, Rcpp, knitr, rmarkdown, kableExtra |
Published: | 2024-03-23 |
DOI: | 10.32614/CRAN.package.PFIM |
Author: | France Mentré [aut], Romain Leroux [aut, cre], Jérémy Seurat [aut], Lucie Fayette [aut], Emmanuelle Comets [ctb], Sylvie Retout [ctb] |
Maintainer: | Romain Leroux <romain.leroux at inserm.fr> |
License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
URL: | http://www.pfim.biostat.fr/ |
NeedsCompilation: | no |
CRAN checks: | PFIM results |
Reference manual: | PFIM.pdf |
Vignettes: |
Design evaluation and optimization in discrete space Design evaluation and optimization in continuous space Library of models |
Package source: | PFIM_6.0.3.tar.gz |
Windows binaries: | r-devel: PFIM_6.0.3.zip, r-release: PFIM_6.0.3.zip, r-oldrel: PFIM_6.0.3.zip |
macOS binaries: | r-release (arm64): PFIM_6.0.3.tgz, r-oldrel (arm64): PFIM_6.0.3.tgz, r-release (x86_64): PFIM_6.0.3.tgz, r-oldrel (x86_64): PFIM_6.0.3.tgz |
Old sources: | PFIM archive |
Please use the canonical form https://CRAN.R-project.org/package=PFIM to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.