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depower: Power Analysis for Differential Expression Studies

Provides a convenient framework to simulate, test, power, and visualize data for differential expression studies with lognormal or negative binomial outcomes. Supported designs are two-sample comparisons of independent or dependent outcomes. Power may be summarized in the context of controlling the per-family error rate or family-wise error rate. Negative binomial methods are described in Yu, Fernandez, and Brock (2017) <doi:10.1186/s12859-017-1648-2> and Yu, Fernandez, and Brock (2020) <doi:10.1186/s12859-020-3541-7>.

Version: 2024.12.4
Depends: R (≥ 4.2.0)
Imports: Rdpack, stats, mvnfast, glmmTMB, dplyr, multidplyr, ggplot2, scales
Suggests: tinytest, rmarkdown
Published: 2024-12-08
DOI: 10.32614/CRAN.package.depower
Author: Brett Klamer ORCID iD [aut, cre], Lianbo Yu ORCID iD [aut]
Maintainer: Brett Klamer <code at brettklamer.com>
License: MIT + file LICENSE
URL: https://brettklamer.com/work/depower/, https://bitbucket.org/bklamer/depower/
NeedsCompilation: no
Language: en-US
Citation: depower citation info
Materials: README NEWS
CRAN checks: depower results

Documentation:

Reference manual: depower.pdf

Downloads:

Package source: depower_2024.12.4.tar.gz
Windows binaries: r-devel: depower_2024.12.4.zip, r-release: depower_2024.12.4.zip, r-oldrel: depower_2024.12.4.zip
macOS binaries: r-release (arm64): depower_2024.12.4.tgz, r-oldrel (arm64): depower_2024.12.4.tgz, r-release (x86_64): depower_2024.12.4.tgz, r-oldrel (x86_64): depower_2024.12.4.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=depower to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.