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grantham: Calculate the Grantham Distance

A minimal set of routines to calculate the Grantham distance <doi:10.1126/science.185.4154.862>. The Grantham distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.

Version: 0.1.2
Depends: R (≥ 2.10)
Imports: tibble, vctrs, dplyr
Suggests: spelling, testthat (≥ 3.0.0)
Published: 2024-07-30
DOI: 10.32614/CRAN.package.grantham
Author: Ramiro Magno ORCID iD [aut, cre], Isabel Duarte ORCID iD [aut], Ana-Teresa Maia ORCID iD [aut], University of Algarve [fnd], CINTESIS [fnd], Pattern Institute [cph, fnd]
Maintainer: Ramiro Magno <rmagno at pattern.institute>
BugReports: https://github.com/patterninstitute/grantham/issues
License: MIT + file LICENSE
URL: https://www.pattern.institute/grantham/, https://github.com/patterninstitute/grantham
NeedsCompilation: no
Language: en-US
Materials: README NEWS
CRAN checks: grantham results

Documentation:

Reference manual: grantham.pdf

Downloads:

Package source: grantham_0.1.2.tar.gz
Windows binaries: r-devel: grantham_0.1.2.zip, r-release: grantham_0.1.2.zip, r-oldrel: grantham_0.1.2.zip
macOS binaries: r-release (arm64): grantham_0.1.2.tgz, r-oldrel (arm64): grantham_0.1.2.tgz, r-release (x86_64): grantham_0.1.2.tgz, r-oldrel (x86_64): grantham_0.1.2.tgz
Old sources: grantham archive

Reverse dependencies:

Reverse imports: agvgd

Linking:

Please use the canonical form https://CRAN.R-project.org/package=grantham to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.