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graphicalMCP: Graphical Multiple Comparison Procedures

Multiple comparison procedures (MCPs) control the familywise error rate in clinical trials. Graphical MCPs include many commonly used procedures as special cases; see Bretz et al. (2011) <doi:10.1002/bimj.201000239>, Lu (2016) <doi:10.1002/sim.6985>, and Xi et al. (2017) <doi:10.1002/bimj.201600233>. This package is a low-dependency implementation of graphical MCPs which allow mixed types of tests. It also includes power simulations and visualization of graphical MCPs.

Version: 0.2.6
Depends: R (≥ 4.1.0)
Imports: matrixStats, mvtnorm
Suggests: bench, dplyr, forcats, ggplot2, gMCP, gt, here, htmltools, igraph, knitr, lrstat, prompt, rmarkdown, scales, testthat (≥ 3.0.0), tibble, tictoc, tidyr, xfun
Published: 2024-11-08
DOI: 10.32614/CRAN.package.graphicalMCP
Author: Dong Xi [aut, cre], Ethan Brockmann [aut], Gilead Sciences, Inc. [cph, fnd]
Maintainer: Dong Xi <dong.xi1 at gilead.com>
BugReports: https://github.com/openpharma/graphicalMCP/issues
License: Apache License (≥ 2)
URL: https://github.com/openpharma/graphicalMCP
NeedsCompilation: no
Citation: graphicalMCP citation info
Materials: README NEWS
CRAN checks: graphicalMCP results

Documentation:

Reference manual: graphicalMCP.pdf
Vignettes: Graphical multiple comparison procedures based on the closure principle (source, R code)
Comparisons with other packages (source, R code)
Rationales to generate the closure and the weighting strategy of a graph (source, R code)
Glossary (source, R code)
Common multiple comparison procedures illustrated using graphicalMCP (source, R code)
Get started (source, R code)
Sequentially rejective graphical multiple comparison procedures based on Bonferroni tests (source, R code)

Downloads:

Package source: graphicalMCP_0.2.6.tar.gz
Windows binaries: r-devel: graphicalMCP_0.2.5.zip, r-release: graphicalMCP_0.2.6.zip, r-oldrel: graphicalMCP_0.2.6.zip
macOS binaries: r-release (arm64): graphicalMCP_0.2.6.tgz, r-oldrel (arm64): graphicalMCP_0.2.6.tgz, r-release (x86_64): graphicalMCP_0.2.6.tgz, r-oldrel (x86_64): graphicalMCP_0.2.6.tgz
Old sources: graphicalMCP archive

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.