htrSPRanalysis: Analysis of Surface Plasmon Resonance Data

Analysis of Surface Plasmon Resonance (SPR) and Biolayer Interferometry data, with automations for high-throughput SPR. This version of the package fits the 1: 1 binding model, with and without bulkshift. It offers optional local or global Rmax fitting. The user must provide a sample sheet and a Carterra output file in Carterra's current format. There is a utility function to convert from Carterra's old output format. The user may run a custom pipeline or use the provided 'Runscript', which will produce a pdf file containing fitted Rmax, ka, kd and standard errors, a plot of the sensorgram and fits, and a plot of residuals. The script will also produce a .csv file with all of the relevant parameters for each spot on the SPR chip.

Version:	0.1.0
Imports:	magrittr, readxl, openxlsx, minpack.lm, zoo, stats, gridExtra, grid, parallel, readr, rlang, dplyr, stringr, tidyselect, ggplot2, purrr, forcats, tibble, tidyr
Suggests:	knitr, rmarkdown, markdown, qpdf
Published:	2024-08-26
DOI:	10.32614/CRAN.package.htrSPRanalysis
Author:	Janice McCarthy Developer [aut, cre, cph], Kan Li Dev [aut], S. Moses Dennison [aut], Georgia D. Tomaras [aut]
Maintainer:	Janice McCarthy Developer <janice.mccarthy at duke.edu>
License:	GPL (≥ 3)
NeedsCompilation:	no
Materials:	README
CRAN checks:	htrSPRanalysis results

Documentation:

Reference manual:	htrSPRanalysis.pdf
Vignettes:	Introduction to htSPRanalysis (source, R code)

Downloads:

Package source:	htrSPRanalysis_0.1.0.tar.gz
Windows binaries:	r-devel: htrSPRanalysis_0.1.0.zip, r-release: htrSPRanalysis_0.1.0.zip, r-oldrel: htrSPRanalysis_0.1.0.zip
macOS binaries:	r-release (arm64): htrSPRanalysis_0.1.0.tgz, r-oldrel (arm64): htrSPRanalysis_0.1.0.tgz, r-release (x86_64): htrSPRanalysis_0.1.0.tgz, r-oldrel (x86_64): htrSPRanalysis_0.1.0.tgz

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