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'Monolix' is a tool for running mixed effects model using 'saem'. This tool allows you to convert 'Monolix' models to 'rxode2' (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) using the form compatible with 'nlmixr2' (Fidler et al (2019) <doi:10.1002/psp4.12445>). If available, the 'rxode2' model will read in the 'Monolix' data and compare the simulation for the population model individual model and residual model to immediately show how well the translation is performing. This saves the model development time for people who are creating an 'rxode2' model manually. Additionally, this package reads in all the information to allow simulation with uncertainty (that is the number of observations, the number of subjects, and the covariance matrix) with a 'rxode2' model. This is complementary to the 'babelmixr2' package that translates 'nlmixr2' models to 'Monolix' and can convert the objects converted from 'monolix2rx' to a full 'nlmixr2' fit. While not required, you can get/install the 'lixoftConnectors' package in the 'Monolix' installation, as described at the following url <https://monolixsuite.slp-software.com/r-functions/2024R1/installation-and-initialization>. When 'lixoftConnectors' is available, 'Monolix' can be used to load its model library instead manually setting up text files (which only works with old versions of 'Monolix').
Version: | 0.0.3 |
Imports: | Rcpp, checkmate, cli, dparser, withr, ggplot2, ggforce, stringi, crayon, lotri, magrittr, rxode2 (≥ 3.0.0) |
LinkingTo: | dparser, rxode2, Rcpp |
Suggests: | devtools, testthat (≥ 3.0.0), xgxr, vdiffr, lixoftConnectors |
Published: | 2024-10-24 |
DOI: | 10.32614/CRAN.package.monolix2rx |
Author: | Matthew Fidler [aut, cre], Justin Wilkins [ctb] |
Maintainer: | Matthew Fidler <matthew.fidler at gmail.com> |
License: | MIT + file LICENSE |
URL: | https://nlmixr2.github.io/monolix2rx/, https://github.com/nlmixr2/monolix2rx/ |
NeedsCompilation: | yes |
Materials: | README NEWS |
CRAN checks: | monolix2rx results |
Reference manual: | monolix2rx.pdf |
Package source: | monolix2rx_0.0.3.tar.gz |
Windows binaries: | r-devel: monolix2rx_0.0.3.zip, r-release: monolix2rx_0.0.3.zip, r-oldrel: monolix2rx_0.0.3.zip |
macOS binaries: | r-release (arm64): monolix2rx_0.0.3.tgz, r-oldrel (arm64): monolix2rx_0.0.3.tgz, r-release (x86_64): monolix2rx_0.0.3.tgz, r-oldrel (x86_64): monolix2rx_0.0.3.tgz |
Old sources: | monolix2rx archive |
Reverse imports: | babelmixr2 |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.