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Facilities for running simulations from ordinary differential equation ('ODE') models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The 'VODE' and 'LSODA' are in the public domain. The information is available in the inst/COPYRIGHTS.
Version: | 3.0.2 |
Depends: | R (≥ 4.0.0) |
Imports: | PreciseSums (≥ 0.7), Rcpp (≥ 0.12.3), backports, cli (≥ 2.0.0), checkmate, ggplot2 (≥ 3.4.0), inline, lotri (≥ 1.0.0), magrittr, memoise, methods, rex, sys, tools, utils, dparser (≥ 1.3.1-12), rxode2ll (≥ 2.0.9), data.table (≥ 1.12.4), qs (≥ 0.26.3) |
LinkingTo: | sitmo, lotri (≥ 1.0.0), PreciseSums (≥ 0.7), Rcpp, RcppArmadillo (≥ 0.9.300.2.0), BH, RcppParallel, RcppEigen (≥ 0.3.3.9.2), StanHeaders (≥ 2.21.0.7), dparser (≥ 1.3.1-12) |
Suggests: | Matrix, DT, covr, crayon, curl, digest, dplyr (≥ 0.8.0), ggrepel, gridExtra, htmltools, knitr, learnr, microbenchmark, nlme, remotes, rlang, rmarkdown, scales, shiny, stringi, symengine, testthat, tidyr, usethis, vdiffr (≥ 1.0), withr, xgxr, pillar, tibble, units (≥ 0.6-0), rsconnect, devtools, patchwork, nlmixr2data, lifecycle, kableExtra |
Published: | 2024-10-30 |
DOI: | 10.32614/CRAN.package.rxode2 |
Author: | Matthew L. Fidler [aut, cre], Wenping Wang [aut], Alan Hindmarsh [ctb], Arun Srinivasan [ctb], Awad H. Al-Mohy [ctb], Bill Denney [ctb], Cleve Moler [ctb], David Cooley [ctb], Drew Schmidt [ctb], Ernst Hairer [ctb], Gabriel Staples [ctb], Gerhard Wanner [ctb], Gilbert Stewart [ctb], Goro Fuji [ctb], Hadley Wickham [ctb], Igor Kushnir [ctb], Jack Dongarra [ctb], Jim Bunch [ctb], Kevin Ushey [ctb], Linda Petzold [ctb], Martin Maechler [ctb], Matt Dowle [ctb], Matteo Fasiolo [ctb], Melissa Hallow [aut], Michel Lang [ctb], Morwenn [ctb], Nicholas J. Higham [ctb], Omar Elashkar [ctb], Richard Upton [ctb], Roger B. Sidje [ctb], Simon Frost [ctb], Yu Feng [ctb], Zufar Mulyukov [ctb] |
Maintainer: | Matthew L. Fidler <matthew.fidler at gmail.com> |
BugReports: | https://github.com/nlmixr2/rxode2/issues/ |
License: | GPL (≥ 3) |
Copyright: | see file COPYRIGHTS |
URL: | https://nlmixr2.github.io/rxode2/, https://github.com/nlmixr2/rxode2/ |
NeedsCompilation: | yes |
Language: | en-US |
Citation: | rxode2 citation info |
Materials: | README NEWS |
In views: | DifferentialEquations, HighPerformanceComputing, MixedModels, Pharmacokinetics |
CRAN checks: | rxode2 results |
Reference manual: | rxode2.pdf |
Vignettes: |
rxode2 ODE solving syntax (source) |
Package source: | rxode2_3.0.2.tar.gz |
Windows binaries: | r-devel: rxode2_3.0.2.zip, r-release: rxode2_3.0.2.zip, r-oldrel: rxode2_3.0.2.zip |
macOS binaries: | r-release (arm64): rxode2_3.0.2.tgz, r-oldrel (arm64): rxode2_3.0.2.tgz, r-release (x86_64): rxode2_3.0.2.tgz, r-oldrel (x86_64): rxode2_3.0.2.tgz |
Old sources: | rxode2 archive |
Reverse imports: | babelmixr2, monolix2rx, nlmixr2, nlmixr2est, nlmixr2extra, nlmixr2lib, nlmixr2plot, nlmixr2rpt, nonmem2rx, posologyr, ruminate |
Reverse linking to: | babelmixr2, monolix2rx, nlmixr2est, nonmem2rx |
Reverse suggests: | campsis, ggPMX |
Please use the canonical form https://CRAN.R-project.org/package=rxode2 to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.