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Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>). This package is for support functions like preconditioned fits <doi:10.1208/s12248-016-9866-5>, boostrap and stepwise covariate selection.
Version: | 3.0.1 |
Depends: | R (≥ 4.0) |
Imports: | checkmate, cli (≥ 3.4.0), crayon, data.table, digest, dplyr, ggplot2, ggtext, knitr, lotri, methods, nlme, nlmixr2est (≥ 2.1.1), Rcpp, rxode2 (≥ 2.0.10), stats, symengine, utils |
LinkingTo: | Rcpp, RcppArmadillo |
Suggests: | brms, nlmixr2data, testthat (≥ 3.0.0), withr, devtools |
Published: | 2024-10-29 |
DOI: | 10.32614/CRAN.package.nlmixr2extra |
Author: | Matthew Fidler [aut, cre], Vipul Mann [aut], Vishal Sarsani [aut], Christian Bartels [ctb], Bill Denney [aut] |
Maintainer: | Matthew Fidler <matthew.fidler at gmail.com> |
BugReports: | https://github.com/nlmixr2/nlmixr2extra/issues/ |
License: | GPL (≥ 3) |
URL: | https://nlmixr2.github.io/nlmixr2extra/, https://github.com/nlmixr2/nlmixr2extra/ |
NeedsCompilation: | yes |
Citation: | nlmixr2extra citation info |
Materials: | README NEWS |
CRAN checks: | nlmixr2extra results |
Reference manual: | nlmixr2extra.pdf |
Package source: | nlmixr2extra_3.0.1.tar.gz |
Windows binaries: | r-devel: nlmixr2extra_3.0.1.zip, r-release: nlmixr2extra_3.0.1.zip, r-oldrel: nlmixr2extra_3.0.1.zip |
macOS binaries: | r-release (arm64): nlmixr2extra_3.0.1.tgz, r-oldrel (arm64): nlmixr2extra_3.0.1.tgz, r-release (x86_64): nlmixr2extra_3.0.1.tgz, r-oldrel (x86_64): nlmixr2extra_3.0.1.tgz |
Old sources: | nlmixr2extra archive |
Reverse imports: | nlmixr2, nlmixr2plot, nlmixr2rpt |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.