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Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).
Version: | 3.0.1 |
Depends: | nlmixr2data |
Imports: | nlmixr2est (≥ 2.2.2), nlmixr2extra (≥ 2.0.10), rxode2 (≥ 2.1.3), lotri (≥ 0.4.3), nlmixr2plot (≥ 2.0.8), magrittr, crayon, cli |
Suggests: | rmarkdown, knitr, devtools, ggplot2, testthat, n1qn1, withr |
Published: | 2024-10-28 |
DOI: | 10.32614/CRAN.package.nlmixr2 |
Author: | Matthew Fidler [aut, cre], Yuan Xiong [ctb], Rik Schoemaker [ctb], Justin Wilkins [ctb], Wenping Wang [ctb], Mirjam Trame [ctb], Huijuan Xu [ctb], John Harrold [ctb], Bill Denney [ctb], Theodoros Papathanasiou [ctb], Teun Post [ctb], Richard Hooijmaijers [ctb] |
Maintainer: | Matthew Fidler <matthew.fidler at gmail.com> |
BugReports: | https://github.com/nlmixr2/nlmixr2/issues/ |
License: | GPL (≥ 3) |
URL: | https://nlmixr2.org/, https://github.com/nlmixr2/nlmixr2/ |
NeedsCompilation: | no |
Citation: | nlmixr2 citation info |
Materials: | README NEWS |
In views: | DifferentialEquations, HighPerformanceComputing, MixedModels, Pharmacokinetics |
CRAN checks: | nlmixr2 results |
Reference manual: | nlmixr2.pdf |
Package source: | nlmixr2_3.0.1.tar.gz |
Windows binaries: | r-devel: nlmixr2_3.0.1.zip, r-release: nlmixr2_3.0.1.zip, r-oldrel: nlmixr2_3.0.1.zip |
macOS binaries: | r-release (arm64): nlmixr2_3.0.1.tgz, r-oldrel (arm64): nlmixr2_3.0.1.tgz, r-release (x86_64): nlmixr2_3.0.1.tgz, r-oldrel (x86_64): nlmixr2_3.0.1.tgz |
Old sources: | nlmixr2 archive |
Reverse depends: | babelmixr2 |
Reverse imports: | nlmixr2rpt |
Reverse suggests: | ggPMX, tidyvpc, xpose.nlmixr2 |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.