posologyr: Individual Dose Optimization using Population Pharmacokinetics

Optimize drug regimens through model-informed precision dosing, using individual pharmacokinetic (PK) and pharmacokinetic-pharmacodynamic (PK-PD) profiles. By integrating therapeutic drug monitoring (TDM) data with population models, 'posologyr' provides accurate posterior estimates and enables the calculation of personalized dosing regimens. The empirical Bayes estimates are computed following the method described by Kang et al. (2012) <doi:10.4196/kjpp.2012.16.2.97>.

Version:	1.2.7
Depends:	R (≥ 3.5.0)
Imports:	rxode2, stats, mvtnorm, data.table
Suggests:	lotri, rmarkdown, testthat (≥ 3.0.0), ggplot2, magrittr, tidyr
Published:	2024-09-13
DOI:	10.32614/CRAN.package.posologyr
Author:	Cyril Leven [aut, cre, cph], Matthew Fidler [ctb], Emmanuelle Comets [ctb], Audrey Lavenu [ctb], Marc Lavielle [ctb]
Maintainer:	Cyril Leven <cyril.leven at chu-brest.fr>
BugReports:	https://github.com/levenc/posologyr/issues
License:	AGPL-3
URL:	https://levenc.github.io/posologyr/, https://github.com/levenc/posologyr
NeedsCompilation:	no
Citation:	posologyr citation info
Materials:	README NEWS
In views:	Pharmacokinetics
CRAN checks:	posologyr results

Documentation:

Reference manual:

posologyr.pdf

Downloads:

Package source:	posologyr_1.2.7.tar.gz
Windows binaries:	r-devel: posologyr_1.2.7.zip, r-release: posologyr_1.2.7.zip, r-oldrel: posologyr_1.2.7.zip
macOS binaries:	r-release (arm64): posologyr_1.2.7.tgz, r-oldrel (arm64): posologyr_1.2.7.tgz, r-release (x86_64): posologyr_1.2.7.tgz, r-oldrel (x86_64): posologyr_1.2.7.tgz
Old sources:	posologyr archive

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