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pmxTools: Pharmacometric and Pharmacokinetic Toolkit

Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero- and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008) <http://lixoft.com/wp-content/uploads/2016/03/PKPDlibrary.pdf>); parametric simulation from NONMEM-generated parameter estimates and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).

Version: 1.3
Depends: R (≥ 3.50), patchwork
Imports: ggplot2, chron, xml2, dplyr (≥ 0.8.5), tibble, gghalves, ggdist, scales, MASS, stringr, PKNCA, magrittr, data.tree
Suggests: testthat, vdiffr, knitr, rmarkdown
Published: 2023-02-21
DOI: 10.32614/CRAN.package.pmxTools
Author: Justin Wilkins ORCID iD [aut, cre], Bill Denney ORCID iD [aut], Rik Schoemaker [aut], Satyaprakash Nayak [ctb], Leonid Gibiansky [ctb], Andrew Hooker [ctb], E. Niclas Jonsson [ctb], Mats O. Karlsson [ctb], John Johnson [ctb]
Maintainer: Justin Wilkins <justin.wilkins at occams.com>
Contact: Justin Wilkins <justin.wilkins@occams.com>
BugReports: https://github.com/kestrel99/pmxTools/issues
License: GPL-2
URL: https://github.com/kestrel99/pmxTools
NeedsCompilation: no
Materials: README NEWS
In views: Pharmacokinetics
CRAN checks: pmxTools results

Documentation:

Reference manual: pmxTools.pdf
Vignettes: Drawing PK curves with pmxTools

Downloads:

Package source: pmxTools_1.3.tar.gz
Windows binaries: r-devel: pmxTools_1.3.zip, r-release: pmxTools_1.3.zip, r-oldrel: pmxTools_1.3.zip
macOS binaries: r-release (arm64): pmxTools_1.3.tgz, r-oldrel (arm64): pmxTools_1.3.tgz, r-release (x86_64): pmxTools_1.3.tgz, r-oldrel (x86_64): pmxTools_1.3.tgz
Old sources: pmxTools archive

Reverse dependencies:

Reverse suggests: mrgsolve, PKNCA

Linking:

Please use the canonical form https://CRAN.R-project.org/package=pmxTools to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.