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When multiple Cox proportional hazard models are performed on clinical data (month or year and status) and a set of differential expressions of genes, the results (Hazard risks, z-scores and p-values) can be used to create gene-expression signatures. Weights are calculated using the survival p-values of genes and are utilized to calculate expression values of the signature across the selected genes in all patients in a cohort. A Single or multiple univariate or multivariate Cox proportional hazard survival analyses of the patients in one cohort can be performed by using the gene-expression signature and visualized using our survival plots.
Version: | 1.0.0 |
Depends: | R (≥ 3.5.0) |
Imports: | stats, utils, graphics, grDevices, dplyr, forestplot, gplots, gtools, survival, survminer, ggplot2 |
Suggests: | Rmisc |
Published: | 2023-07-19 |
DOI: | 10.32614/CRAN.package.signatureSurvival |
Author: | Yuan-De Tan [aut, cre], Yuguang Ban [ctb] |
Maintainer: | Yuan-De Tan <tanyuande at gmail.com> |
License: | GPL (≥ 3) |
NeedsCompilation: | no |
CRAN checks: | signatureSurvival results |
Reference manual: | signatureSurvival.pdf |
Package source: | signatureSurvival_1.0.0.tar.gz |
Windows binaries: | r-devel: signatureSurvival_1.0.0.zip, r-release: signatureSurvival_1.0.0.zip, r-oldrel: signatureSurvival_1.0.0.zip |
macOS binaries: | r-release (arm64): signatureSurvival_1.0.0.tgz, r-oldrel (arm64): signatureSurvival_1.0.0.tgz, r-release (x86_64): signatureSurvival_1.0.0.tgz, r-oldrel (x86_64): signatureSurvival_1.0.0.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.