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Provides functions for the evaluation of surrogate endpoints when both the surrogate and the true endpoint are failure time variables. The approaches implemented are: (1) the two-step approach (Burzykowski et al, 2001) <doi:10.1111/1467-9876.00244> with a copula model (Clayton, Plackett, Hougaard) at the first step and either a linear regression of log-hazard ratios at the second step (either adjusted or not for measurement error); (2) mixed proportional hazard models estimated via mixed Poisson GLM (Rotolo et al, 2017 <doi:10.1177/0962280217718582>).
Version: | 1.1.26 |
Depends: | R (≥ 3.5.0) |
Imports: | copula, eha, grDevices, lme4, MASS, Matrix, msm, mvmeta, optimx, parallel, parfm, stats, survival |
Suggests: | R.rsp, testthat (≥ 3.0.0) |
Published: | 2023-04-14 |
DOI: | 10.32614/CRAN.package.surrosurv |
Author: | Federico Rotolo [aut], Xavier Paoletti [ctb], Marc Buyse [ctb], Tomasz Burzykowski [ctb], Stefan Michiels [ctb], Dan Chaltiel [cre] |
Maintainer: | Dan Chaltiel <dan.chaltiel at gustaveroussy.fr> |
BugReports: | https://github.com/Oncostat/surrosurv/issues/ |
License: | GPL-2 |
URL: | https://github.com/Oncostat/surrosurv |
NeedsCompilation: | no |
Materials: | README NEWS |
CRAN checks: | surrosurv results |
Reference manual: | surrosurv.pdf |
Vignettes: |
Validation of time-to-event surrogate endpoints using the surrosurv package |
Package source: | surrosurv_1.1.26.tar.gz |
Windows binaries: | r-devel: surrosurv_1.1.26.zip, r-release: surrosurv_1.1.26.zip, r-oldrel: surrosurv_1.1.26.zip |
macOS binaries: | r-release (arm64): surrosurv_1.1.26.tgz, r-oldrel (arm64): surrosurv_1.1.26.tgz, r-release (x86_64): surrosurv_1.1.26.tgz, r-oldrel (x86_64): surrosurv_1.1.26.tgz |
Old sources: | surrosurv archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.