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tci: Target Controlled Infusion (TCI)

Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.

Version: 0.2.0
Depends: R (≥ 3.6.0)
Imports: ggplot2, stats, utils, truncnorm, mvtnorm, gridExtra, reshape, reshape2, xtable, Rcpp, knitr
LinkingTo: Rcpp, RcppArmadillo
Suggests: testthat (≥ 2.1.0), rmarkdown, mrgsolve
Published: 2022-08-15
DOI: 10.32614/CRAN.package.tci
Author: Ryan Jarrett [aut, cre]
Maintainer: Ryan Jarrett <ryantjarrett at gmail.com>
BugReports: https://github.com/jarretrt/tci/issues
License: GPL-2
URL: https://github.com/jarretrt/tci
NeedsCompilation: yes
Materials: README
CRAN checks: tci results

Documentation:

Reference manual: tci.pdf
Vignettes: Custom PK models and algorithms
Introduction to tci package
Population PK models

Downloads:

Package source: tci_0.2.0.tar.gz
Windows binaries: r-devel: tci_0.2.0.zip, r-release: tci_0.2.0.zip, r-oldrel: tci_0.2.0.zip
macOS binaries: r-release (arm64): tci_0.2.0.tgz, r-oldrel (arm64): tci_0.2.0.tgz, r-release (x86_64): tci_0.2.0.tgz, r-oldrel (x86_64): tci_0.2.0.tgz
Old sources: tci archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=tci to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.