AbSolution: Interactive Feature-Based Analysis of AIRR-Seq Data

An interactive framework for the exploration and analysis of adaptive immune receptor repertoire sequencing (AIRR-seq) data. It enables large-scale computation and integrated analysis of sequence-derived features, including physicochemical properties, amino acid descriptor sets, sequence motifs, compositional patterns, and somatic hypermutation metrics. The application supports multiscale analysis across sequences, clones, and repertoires, with interactive visualizations and statistical feature selection. 'AbSolution' also facilitates reproducible research by enabling structured export of data, code, parameters, and computational environments. See <https://github.com/EDS-Bioinformatics-Laboratory/AbSolution> for more details.

Version:	1.0.0
Depends:	R (≥ 4.4.0)
Imports:	alakazam, attachment, benchmarkme, bigassertr, bigparallelr, bigstatsr, Biostrings, bs4Dash, callr, colourpicker, config (≥ 0.3.2), dashboardthemes, data.table, dockerfiler, doParallel, dplyr, DT, foreach, fresh, fs, ggplot2, golem (≥ 0.4.1), grDevices, htmlwidgets, IRanges, iterors, knitr, parallel, Peptides, plotly, pwalign, reactable, rlang, rmarkdown, seqinr, shiny (≥ 1.7.4), shinycssloaders, shinyFiles, shinyjs, shinymanager, shinymeta, shinythemes, shinyWidgets, sortable, stats, stringdist, stringr, sunburstR, tools, umap, upsetjs, utils, viridis, xfun
Suggests:	testthat (≥ 3.0.0)
Published:	2026-04-21
DOI:	10.32614/CRAN.package.AbSolution
Author:	Rodrigo García-Valiente [cre, aut] (email2: rodrigo.garcia.valiente+absolution@email.com), Charisios Triantafyllou [aut], Antoine van Kampen [aut, ths]
Maintainer:	Rodrigo García-Valiente <r.garciavaliente at amsterdamumc.nl>
BugReports:	https://github.com/EDS-Bioinformatics-Laboratory/AbSolution/issues
License:	GPL (≥ 3)
URL:	https://github.com/EDS-Bioinformatics-Laboratory/AbSolution, https://eds-bioinformatics-laboratory.github.io/AbSolution/
NeedsCompilation:	no
Language:	en-US
Materials:	README, NEWS
CRAN checks:	AbSolution results

Documentation:

Reference manual:	AbSolution.html , AbSolution.pdf
Vignettes:	AbSolution (source, R code)

Downloads:

Package source:	AbSolution_1.0.0.tar.gz
Windows binaries:	r-release: AbSolution_1.0.0.zip, r-oldrel: AbSolution_1.0.0.zip
macOS binaries:	r-release (arm64): AbSolution_1.0.0.tgz, r-oldrel (arm64): AbSolution_1.0.0.tgz, r-release (x86_64): AbSolution_1.0.0.tgz, r-oldrel (x86_64): AbSolution_1.0.0.tgz

Linking:

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