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MARVEL: Revealing Splicing Dynamics at Single-Cell Resolution

Alternative splicing represents an additional and underappreciated layer of complexity underlying gene expression profiles. Nevertheless, there remains hitherto a paucity of software to investigate splicing dynamics at single-cell resolution. 'MARVEL' enables splicing analysis of single-cell RNA-sequencing data generated from plate- and droplet-based library preparation methods.

Version: 1.4.0
Depends: R (≥ 3.5.0)
Imports: ggplot2 (≥ 3.3.2), Matrix (≥ 1.3-3), methods, plyr (≥ 1.8.4), scales (≥ 1.1.1)
Suggests: AnnotationDbi (≥ 1.48.0), Biostrings (≥ 2.56.0), BSgenome (≥ 1.56.0), BSgenome.Hsapiens.NCBI.GRCh38 (≥ 1.3.1000), clusterProfiler (≥ 3.16.0), factoextra (≥ 1.0.7), FactoMineR (≥ 2.3), fitdistrplus (≥ 1.1-1), GenomicRanges (≥ 1.42.0), ggnewscale (≥ 0.4.5), ggrepel (≥ 0.9.1), gridExtra (≥ 2.3), gtools (≥ 3.9.2), IRanges (≥ 2.24.1), kableExtra (≥ 1.3.1), knitr (≥ 1.29), kSamples (≥ 1.2-9), markdown (≥ 1.1), MAST (≥ 1.16.0), org.Hs.eg.db (≥ 3.10.0), org.Mm.eg.db (≥ 3.11.4), parallel, pheatmap (≥ 1.0.12), reshape2 (≥ 1.4.4), rmarkdown (≥ 2.3), S4Vectors (≥ 0.26.1), stringr (≥ 1.4.0), textclean (≥ 0.9.3), twosamples (≥ 1.1.1), wiggleplotr (≥ 1.12.1)
Published: 2022-10-31
DOI: 10.32614/CRAN.package.MARVEL
Author: Sean Wen [aut, cre]
Maintainer: Sean Wen <sean.wenwx at gmail.com>
License: GPL-3
NeedsCompilation: no
CRAN checks: MARVEL results

Documentation:

Reference manual: MARVEL.pdf
Vignettes: MARVEL

Downloads:

Package source: MARVEL_1.4.0.tar.gz
Windows binaries: r-devel: MARVEL_1.4.0.zip, r-release: MARVEL_1.4.0.zip, r-oldrel: MARVEL_1.4.0.zip
macOS binaries: r-release (arm64): MARVEL_1.4.0.tgz, r-oldrel (arm64): MARVEL_1.4.0.tgz, r-release (x86_64): MARVEL_1.4.0.tgz, r-oldrel (x86_64): MARVEL_1.4.0.tgz
Old sources: MARVEL archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=MARVEL to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.