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campsismod: Generic Implementation of a PK/PD Model

A generic, easy-to-use and expandable implementation of a pharmacokinetic (PK) / pharmacodynamic (PD) model based on the S4 class system. This package allows the user to read/write a pharmacometric model from/to files and adapt it further on the fly in the R environment. For this purpose, this package provides an intuitive API to add, modify or delete equations, ordinary differential equations (ODE's), model parameters or compartment properties (like infusion duration or rate, bioavailability and initial values). Finally, this package also provides a useful export of the model for use with simulation packages 'rxode2' and 'mrgsolve'. This package is designed and intended to be used with package 'campsis', a PK/PD simulation platform built on top of 'rxode2' and 'mrgsolve'.

Version: 1.1.1
Depends: R (≥ 4.0.0)
Imports: assertthat, dplyr, magrittr, methods, plyr, purrr, readr, tibble, utils
Suggests: devtools, knitr, pkgdown, rmarkdown, roxygen2, testthat, xfun
Published: 2024-02-16
DOI: 10.32614/CRAN.package.campsismod
Author: Nicolas Luyckx [aut, cre]
Maintainer: Nicolas Luyckx <nicolas.luyckx at calvagone.com>
BugReports: https://github.com/Calvagone/campsismod/issues
License: GPL (≥ 3)
URL: https://github.com/Calvagone/campsismod, https://calvagone.github.io/
NeedsCompilation: no
Language: en-US
Materials: README NEWS
CRAN checks: campsismod results

Documentation:

Reference manual: campsismod.pdf
Vignettes: Get started with CAMPSIS model
Create a minimalist model
Insight on the structural model
Adapt your model
Play with compartment properties
Adapt your parameters
Append a model to another

Downloads:

Package source: campsismod_1.1.1.tar.gz
Windows binaries: r-devel: campsismod_1.1.1.zip, r-release: campsismod_1.1.1.zip, r-oldrel: campsismod_1.1.1.zip
macOS binaries: r-release (arm64): campsismod_1.1.1.tgz, r-oldrel (arm64): campsismod_1.1.1.tgz, r-release (x86_64): campsismod_1.1.1.tgz, r-oldrel (x86_64): campsismod_1.1.1.tgz
Old sources: campsismod archive

Reverse dependencies:

Reverse depends: campsis

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.