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cubar: Codon Usage Bias Analysis

A suite of functions for rapid and flexible analysis of codon usage bias. It provides in-depth analysis at the codon level, including relative synonymous codon usage (RSCU), tRNA weight calculations, machine learning predictions for optimal or preferred codons, and visualization of codon-anticodon pairing. Additionally, it can calculate various gene- specific codon indices such as codon adaptation index (CAI), effective number of codons (ENC), fraction of optimal codons (Fop), tRNA adaptation index (tAI), mean codon stabilization coefficients (CSCg), and GC contents (GC/GC3s/GC4d). It also supports both standard and non-standard genetic code tables found in NCBI, as well as custom genetic code tables.

Version: 1.0.0
Depends: R (≥ 4.1.0)
Imports: Biostrings (≥ 2.60.0), IRanges (≥ 2.34.0), data.table (≥ 1.14.0), ggplot2 (≥ 3.3.5), rlang (≥ 0.4.11)
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2024-08-01
DOI: 10.32614/CRAN.package.cubar
Author: Hong Zhang ORCID iD [aut, cre], Bu Zi [aut]
Maintainer: Hong Zhang <mt1022.dev at gmail.com>
BugReports: https://github.com/mt1022/cubar/issues
License: MIT + file LICENSE
URL: https://github.com/mt1022/cubar, https://mt1022.github.io/cubar/
NeedsCompilation: no
Materials: README NEWS
CRAN checks: cubar results

Documentation:

Reference manual: cubar.pdf
Vignettes: Introduction (source, R code)
Non-standard genetic code (source, R code)

Downloads:

Package source: cubar_1.0.0.tar.gz
Windows binaries: r-devel: cubar_1.0.0.zip, r-release: cubar_1.0.0.zip, r-oldrel: cubar_1.0.0.zip
macOS binaries: r-release (arm64): cubar_1.0.0.tgz, r-oldrel (arm64): cubar_1.0.0.tgz, r-release (x86_64): cubar_1.0.0.tgz, r-oldrel (x86_64): cubar_1.0.0.tgz
Old sources: cubar archive

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.