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goldilocks: Goldilocks Adaptive Trial Designs for Time-to-Event Endpoints

Implements the Goldilocks adaptive trial design for a time to event outcome using a piecewise exponential model and conjugate Gamma prior distributions. The method closely follows the article by Broglio and colleagues <doi:10.1080/10543406.2014.888569>, which allows users to explore the operating characteristics of different trial designs.

Version: 0.4.0
Depends: R (≥ 3.6.0), survival
Imports: dplyr, parallel, pbmcapply, PWEALL, Rcpp, rlang, stats
LinkingTo: BH, Rcpp
Suggests: covr, testthat (≥ 3.0.0), knitr, rmarkdown
Published: 2025-01-08
DOI: 10.32614/CRAN.package.goldilocks
Author: Graeme L. Hickey ORCID iD [aut, cre], Ying Wan [aut], Thevaa Chandereng ORCID iD [aut] (bayesDP code as a template), Becton, Dickinson and Company [cph], Tim Kacprowski [ctb] (For code from fastlogrank R package.)
Maintainer: Graeme L. Hickey <graemeleehickey at gmail.com>
BugReports: https://github.com/graemeleehickey/goldilocks/issues
License: GPL-3
URL: https://github.com/graemeleehickey/goldilocks
NeedsCompilation: yes
Language: en-US
Materials: README NEWS
CRAN checks: goldilocks results

Documentation:

Reference manual: goldilocks.pdf
Vignettes: Example: Two-armed RCT (source, R code)

Downloads:

Package source: goldilocks_0.4.0.tar.gz
Windows binaries: r-devel: goldilocks_0.4.0.zip, r-release: goldilocks_0.4.0.zip, r-oldrel: goldilocks_0.4.0.zip
macOS binaries: r-release (arm64): goldilocks_0.4.0.tgz, r-oldrel (arm64): goldilocks_0.4.0.tgz, r-release (x86_64): goldilocks_0.4.0.tgz, r-oldrel (x86_64): goldilocks_0.4.0.tgz
Old sources: goldilocks archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=goldilocks to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.