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In bulk epigenome/transcriptome experiments, molecular expression is measured in a tissue, which is a mixture of multiple types of cells. This package tests association of a disease/phenotype with a molecular marker for each cell type. The proportion of cell types in each sample needs to be given as input. The package is applicable to epigenome-wide association study (EWAS) and differential gene expression analysis. Takeuchi and Kato (submitted) "omicwas: cell-type-specific epigenome-wide and transcriptome association study".
Version: | 0.8.0 |
Depends: | R (≥ 3.6.0) |
Imports: | broom, data.table, dplyr, ff, glmnet, magrittr, MASS, matrixStats, parallel, purrr, rlang, tidyr |
Suggests: | testthat, knitr, rmarkdown |
Published: | 2020-10-08 |
DOI: | 10.32614/CRAN.package.omicwas |
Author: | Fumihiko Takeuchi [aut, cre] |
Maintainer: | Fumihiko Takeuchi <fumihiko at takeuchi.name> |
BugReports: | https://github.com/fumi-github/omicwas/issues |
License: | GPL-3 |
URL: | https://github.com/fumi-github/omicwas |
NeedsCompilation: | no |
Materials: | README |
In views: | Omics |
CRAN checks: | omicwas results |
Reference manual: | omicwas.pdf |
Vignettes: |
Introduction to omicwas |
Package source: | omicwas_0.8.0.tar.gz |
Windows binaries: | r-devel: omicwas_0.8.0.zip, r-release: omicwas_0.8.0.zip, r-oldrel: omicwas_0.8.0.zip |
macOS binaries: | r-release (arm64): omicwas_0.8.0.tgz, r-oldrel (arm64): omicwas_0.8.0.tgz, r-release (x86_64): omicwas_0.8.0.tgz, r-oldrel (x86_64): omicwas_0.8.0.tgz |
Old sources: | omicwas archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.